Does Growth Hormone Have Anti-Aging Properties?
It is quite true that we are all going to get old. As a matter of fact, the generation of baby boomers is quickly approaching their mid-fifties, and the number of elderly people in America will continue to increase for another generation. Why then, do we have to resign to growing old in the same way that previous generations were forced to in the ages before us? Must we be weak, frail,fatigued, depressed? Living in fear to take a walk in the park for fear that we may fall?
It is atruism that youth is wasted on those who are young. If such a saying is true, why should the opposite statement also be true? Why must wealth and experience be wasted upon those that are old?Should not older men and women be able to retain their enthusiasm and energy in a grand effort to enjoy their autumn years?
We do not have to take age lying down! We here at the Conscious Evolution Medical Institute have learned that old age is largely a state of mind that has been induced by hormonal deficiencies. It is a state in which the hormones we so enjoyed in our youth have become less bountiful. It makes logical sense that with hrt hormone replacement therapy many of these symptoms can be alleviated or reversed.
One of the most impressive hormones that can be regained through Bio identical Hormone Replacement therapy is Human Growth Hormone. It can allow an older woman or gentleman to live a healthier, longer, and more active life. The greatest point to be made about Human Growth Hormone is that it truly is not all that fantastic of a concept.Growth Hormone is naturally produced by the body, and it is produced in large quantities when we are in our youth. The longer we can retain Growth Hormone, the more we can slow down many of the devastating effects of aging.
It makes perfect sense. Growth Hormone is vital to growth processes within the body. GH supplement is provided to young children who are maligned with slow skeletal growth, and it allows them to grow taller than they would without treatment. The problem is that Human Growth Hormone levels drop at a steady rate in all men and women after they enter adulthood. After decades of research, we now know that Human Growth Hormone provides significant benefits throughout the lifespan. For this reason, we must conclude that Growth Hormone is vital for the maintenance and rejuvenation of the body in adulthood. Research regarding the effect of Growth HRT upon elderly patients provides evidence that the main role of the hormone in adulthood is to allow one to live a longer, healthier life of higher quality.
Where does Human Growth Hormone Originate?
Human Growth Hormone is produced in the anterior area of the pituitary gland which is buried deep within the brain. Human Growth Hormone is a microscopic protein molecule. It has chemical similarities with insulin, though HGH is secreted in brief, sharp pulses after a person exercises or in the initial hours of rest. Human Growth Hormone only stays in the blood stream for a few minutes. For this reason, it in incredibly difficult to measure Human Growth Hormone in serum. Though it does not remain in the blood stream for long, HGH binds to the liver which turns some of the hormone into Somatomedin-C, which is also known well by the name Insulin-Like Growth Factor I (IGF-1) Since IGF-I stays in the blood for up to one and a half days, a blood sample that contains IGF-I proves that HGH is being produced. Normal IGF-I levels in the blood tend to appear in volumes of 200 to 450 ng/ml. However, one third of men and women that are over the age of fifty display levels of HGH that are lower than 200 ng/ml. During puberty, Human Growth Hormone levels are at their peak and IGF-I reaches levels of 600-800 ng/ml or even higher. In normal women and men under the age of forty,less than five percent have levels of HGH that are below 250 ng/ml! After the age of 40 many women and men have a level of Human Growth Hormone that is similar to that of an octogenarian! Human Growth Hormone may be the means by which we can age gracefully.
When IGF-I levels drop under the baseline adult range, energy levels and bone and muscle strength tend to decrease as well. Cell regrowth, tissue repair, vital organ repair, general rejuvenate ability, enzyme production, and hair, skin, and nail revitalization will begin to occur less effectively
Though decreased levels of Human Growth Hormone and increased age are certainly directly correlated, those who lose full function of the pituitary gland, whether through accident, infection, or surgery,will immediately begin to be maligned with acute ill effects.
It is vital to understand that natural HGH will inevitably decline with age!
In those who are utterly lacking a functional pituitary, body composition changes and a shift occurs where the amount of fat increases by7-25%. Lean mass of the body decreases at a similar rate. Mass and strength of the muscles diminish as well. Studies in regard to bone density show that in those patients with no pituitary input, it seems as though an individual ages by around 15 years by analysis of the density of both the long bones and the spinal bones. As Human Growth Hormone flags, weight increases of as much as fifty pounds occur. Beyond this, there are issues regarding cholesterol as well. Levels of triglycerides go up, and good HDL cholesterol suffers. Cardiovascular complications occur more often, which could be related to the thickening of the vascular walls of the heart.Decreased output by the heart leads to further problems.
Hormonal in sufficiencies such as these often lead to people such as these to report a serious decline in their capacity to exercise, and they often suffer from cardiovascular disease, which leads to early mortality. Also, they report issues with loneliness, depression,focus, and fatigue. In general, they just suffer from a general lack of well-being.
Hope on the Horizon: Food and Drug Administration approves Human Growth Hormone for Use by Adults
Recombinant HGH has recently gained approval by the FDA for women and men of adulthood for the therapy of Growth Hormone Deficiency and hypopituitarism. If a person suffers from hypopituitarism, Human Growth Hormone therapy is compatible under the majority of insurance policies. After being approved for therapy, patients are administered Human Growth Hormone treatment and testing under professional supervision. Our experience and the revelations of research provide ample evidence that Human Growth Hormone Replacement Therapy offers benefits to those that have insufficient levels of Growth Hormone. This deficiency is often referred to as Somatotropin Deficiency Syndrome. The Conscious Evolution Medical Institute also provides Human Growth Hormone treatment for patients who suffer from Somatomedin-C (Insulin-Like Growth Factor-1) levels under 200 ng/ml that are approved in our Internal Review Board registry, but these patients are required to pay for their treatment.
Please realize that by undergoing a global hormone replacement regimen,administering progesterone, estrogen, testosterone, thyroid,pregnenolone, or DHEA (other vital hormones which a patient may beco-deficient) when necessary in addition to Human Growth Hormone,one can minimize the costs, side-effects, and dosage of treatment.
Growth Hormone Replacement Therapy Changes
Administration of Human Growth Hormone often leads to substantial changes in the composition of the body: lean muscle mass increases as fat mass percentage is reduced. Using Human Growth Hormone at the modest dosage of 0.003 mg/kg over the course of six months was shown to improve lean muscle mass in 24 patients that had a Human Growth Hormone deficiency (1). Improvements in lean muscle mass have been associated with higher levels of protein synthesis, along with muscle function and mass. The percentage of body fat also drops after six months of Human Growth Hormone administration. The most fat is eliminated from the areas of the trunk and the stomach,rather than the legs, neck, and arms. This fact is evidence that Human Growth Hormone replacement treatment can reverse excess stomach fat associated with Human Growth Hormone deficiency, along with reducing risks of heart problems.
Heart Health and Metabolism of Cholesterol
Human Growth Hormone Therapy for adults also shows is believed to have a positive effect upon cholesterol. In new research, it has been shown that brief regimens of Human Growth Hormone Therapy led to reduced LDL (or bad) cholesterol (7) while also boosting heart function and capacity for exercise. Participants showed higher levels of oxygen intake as well as strength during cycling exercise. Human Growth Hormone has been associated with higher levels of muscle mass and stronger and longer action upon the treadmill (8). Recent research by Fazio has shown that those who have experienced heart failure have shown improvement after being given high dosage of Human Growth Hormone Therapy.
Bone Density
Among the most stunning effects of Human Growth Hormone is its effect upon the skeletal system, muscles, and tissues. It provides a significant level of rejuvenation to these systems. Skin health improves, damaged bones heal more effectively, and significant levels of improved muscular strength have been reported during Human Growth Hormone Therapy. Others have reported that signs of aging are fading from their skin. Sometimes hair regrowth occurs in male hormone replacement therapy patients as well as female patients. These changes provide evidence that testosterone, DHEA, and Human Growth Hormone are anabolism (synthesizing) hormones that significantly rehabilitate tissue of the body. Unfortunately, as we age, catabolic processes lead to faster levels of tissue breakdown.Human Growth Hormone combats the catabolic processes of aging.
The most significant way that Human Growth Hormone effects the skeletal system is through its role in enhancing the body's ability to build and repair the bones. Human Growth Hormone stimulates the proliferation of fibroblast (ligament) and osteoblast (bone) cellsin the skeletal system. In recent clinical research using the powerful techniques of single photon absorptiometry and quantitative tomography, marked increases of 4% and 5% were shown in cortical and spinal bone density over the course of twelvemonths of therapy in adults deficient in Human Growth Hormone (4).In conclusion, it seems that the administration of Human Growth Hormone may lead to an enhancement of multiple organ systems of the body through the positive effect it has upon the skeletal system.
More examples of Human Growth Hormone's anabolic effects include muscle gain and increased appetite, increased capacity for exercise,increased capacity of the lungs, and increased would rehabilitation. Many also report that liver spots, also known as senile keratoses, begin to fade after eight weeks of Human Growth Hormone Therapy.
Side-Effects of Low Dosage Human Growth Identical HormoneReplacement Therapy.
Human Growth Hormone dosage is a vital consideration in those who suffer from Human Growth Hormone Deficiency. Over dosage of Human Growth hormone is associated wit many signs of excess Human Growth Hormone. Among these symptoms are hypertension, carpal tunnel, and excess fluid retention. However, by using more modest doses of Human Growth Hormone, it was demonstrated by Bengtsson that only mild side-effects such as slight joint pain and mold fluid retention occur. Only a single case of carpal tunnel was discovered. In each of these cases, further restriction of the Human Growth Hormone dose lead to full elimination of the side-effects. Another clinical study only used a small dose of 0.01mg/kg, which was injected three times each week. In this study,there were zero side-effects reported (8). Many studies provide evidence that says that low dosage Human Growth Identical Hormone replacement therapy generally only causes modest side-effects, if any.
Benefits of Hormone Replacement Therapy with HGH.
Improve Body Composition: Boost muscle mass and reduce fat for a shift in body composition of as much as 20 pounds. This change can lead to higher sex drive, as well as enhanced physical well-being and self perception.
Improve Energy: Human Growth Hormone patients report higher levels of energy without the need for afternoon snacks, stimulants, caffeine,or cigarettes. This energy boost helps them become more confident in their self control and enhances their capacity for exercise.
Improve Focus: An intriguing yet untested potential benefit of Human Growth Hormone is a return of mental focus and enhancement of memory.Since Human Growth Hormone provides improvement to the intracellular and vascular systems which support the cells, it isn't at all surprising that these benefits have been reported in individuals.
The Future
Many fundamental questions remain regarding the exact medical definition and preferred treatment for partial versus total Human Growth Hormone Deficiency. Also, it is not clear whether all of the realized positive effect of full Human Growth Hormone Replacement Therapy will occur in those that undergo low dosage or combination treatments. Even so, is has already been made clear that even small doses that do not result in potential side-effects sufficient level may be sufficient for some to reach their metabolic goals. We hope that our continued clinical evaluations will help lead to more efficient usage of Human Growth Hormone, as well as help reveal more of this wondrous therapy's benefits while eliminating incidence of increased cardiovascular and general morbidity.
Works Cited
Cuneo,Salomon, and Hesp, et al. Treatment effects of Recombinant HGH upon Metabolism and Body Composition among Adults with Growth Hormone Deficiency. New England Journal of Medicine 1989; Issue 321: Pages1797-03.
Bengtsson.Consequences of Growth Hormone Deficiency in Adults. ActaEndocrinoligica 1993; Volume 128: Pages 2-5.
Cuneo,Salomon, Wiles et al. Effects of Human Growth Hormone Treatment Among Adults Whom are Deficient. Applied Physiology Journal 1991;Volume 70: Pages 695-700.
Halloran,Tsatsoulis, Whitehouse et al. Increased Bone Density after Human Growth Hormone Therapy Upon Deficient Adults. Journal of Clinical Endocrine Metabolism 1993;Volume 76: Pages1344-48.
McGauley,Cuneo, Salomon et al. Psych. Self-perception changes due to Growth Hormone Treatment in Adults with Human Growth Hormone Deficiency.Hormone Research 1990; Volume 33(Supplement 4): Pages 52-54.
Bengtsson,Eden, Lonn et al. Therapy of Adults with Human Growth Hormone Deficiency with Recombinant Growth Hormone therapy. Journal of Clinical Endocrine Metabolism 1993;Volume 76:Pages 309-17.
Johnston,Bengtsson. Effects of Growth Hormone and its Deficiency upon Heart and Lipids. Acta Endocrinologica 1993;Volume 128(Supplement2):Pages 69-70.
Amato,Carella, Fazio et al. Heart Structure, Metabolism of Bone, and Body Composition Heart Structure in Growth Hormone-Deficient Adults Effects of Human Growth Hormone Replacement Therapy at Mild Dosage.Journal of Clinical Endocrinology and Metabolism. 1993;Volume77:Pages1671-76.
Fazio,Sabatini, Capaldo, et.al. Test study of GH in the treatment of cardiomyopathy. New England Journal of Medicine. 1996;Volume334:Pages 809-14.
The above information does not provide sufficient evidence to self-diagnose a particular procedure or treatment. It should not lead one to believe that this is the only treatment option available.
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