Active Surveillance: A Key Strategy for Managing Low-Risk Prostate Cancer in American Men

Written by Dr. Jonathan Peterson, Updated on March 22nd, 2025

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Introduction to Prostate Cancer

Prostate cancer is a significant health concern among American men, representing the most common non-skin cancer diagnosed in this demographic. As a disease that predominantly affects older men, understanding the various management strategies is crucial for making informed health decisions. One such strategy that has gained prominence in recent years is active surveillance.

What is Active Surveillance?

Active surveillance is a management approach for prostate cancer that involves closely monitoring the disease rather than immediately pursuing aggressive treatments such as surgery or radiation. This strategy is typically recommended for men with low-risk prostate cancer, where the cancer is not likely to grow quickly or spread. The goal of active surveillance is to avoid or delay the side effects of treatment while still keeping the cancer under control.

Benefits of Active Surveillance

The primary benefit of active surveillance is the reduction of treatment-related side effects. Treatments like surgery and radiation can lead to issues such as urinary incontinence, erectile dysfunction, and bowel problems. By opting for active surveillance, men can maintain their quality of life while still managing their cancer effectively. Additionally, active surveillance allows for a more personalized approach to cancer care, as it can be adjusted based on the progression of the disease.

How Active Surveillance Works

Active surveillance involves regular monitoring through prostate-specific antigen (PSA) tests, digital rectal exams (DRE), and periodic biopsies. These tests help healthcare providers assess the growth and spread of the cancer. If the cancer shows signs of becoming more aggressive, treatment can be initiated promptly. This approach ensures that men receive the necessary interventions without unnecessary exposure to the risks of immediate treatment.

Eligibility for Active Surveillance

Not all men with prostate cancer are candidates for active surveillance. Eligibility is typically based on specific criteria, including the Gleason score, PSA levels, and the number of biopsy cores positive for cancer. Men with low-risk prostate cancer, characterized by a Gleason score of 6 or less, a PSA level of less than 10 ng/mL, and cancer involvement in fewer than one-third of biopsy cores, are often considered suitable for this approach.

Challenges and Considerations

While active surveillance offers several advantages, it also presents challenges. The psychological burden of living with untreated cancer can be significant, and the need for frequent monitoring can be stressful. Additionally, there is a risk of missing the optimal window for treatment if the cancer progresses more rapidly than anticipated. Therefore, it is essential for men considering active surveillance to have thorough discussions with their healthcare providers about the potential risks and benefits.

The Role of Shared Decision-Making

Shared decision-making is a critical component of active surveillance. It involves a collaborative process between the patient and healthcare provider to make informed decisions based on the best available evidence and the patient's values and preferences. This approach ensures that men are actively involved in their care and feel confident in their chosen management strategy.

Conclusion

Active surveillance represents a valuable management option for American men with low-risk prostate cancer. By understanding the benefits, eligibility criteria, and potential challenges, men can make informed decisions about their prostate health. As research continues to evolve, active surveillance is likely to play an increasingly important role in the personalized care of prostate cancer patients, offering a balanced approach to managing this prevalent disease.

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